palmitoylethanolamide cas 544-31-0

描述

PalmitoylethanolamideQuick Details

Chemical Name: Palmitoylethanolamide

CAS NO: 544-31-0

Molecular formula: C18H37NO2

Chemical Structure:

Molecular weight 299.49

Appearance: White powder

Content: 98%

PalmitoylethanolamideTypical Properties

 

Item	Specifications
Active Ingredients
Assay(%, On Dried base)	NLT98.0%
Physical Control
Appearance	Fine Powder
Color	White to Off-White
Identification	Positive
Loss on Drying	1.0% Max
Residue on ignition	0.1% Max
Particle size	D(0.5): 3μm
	D(0.99): 10μm
Excipients	None
Chemical Control
Heavy Metals	NMT10 ppm
Lead(Pb)	NMT1ppm
Arsenic(As)	NMT1ppm
Mercury(Hg)	NMT0.1ppm
Cadmium(Cd)	NMT1ppm
Sulfate(SO4)	NMT0.040%
Chloride(Cl)	NMT0.020%
Solvent Residual	Meeting USP Standard
Microbiological Control
Total Plate Count	10,000cfu/g Max
Yeast Mold	300cfu/g Max
Coliforms	10cfu/g Max
E.Coli	Negative/10g
Salmonella sp.	Negative/25g
Staph Aureus	Negative/10g
Pseudomonas aeruginosa	Negative/25g

Hint

 

The palmitoylethanolamide produced by our company is directly edible and is often used as a raw material for food additives.

PalmitoylethanolamideApplication

1. has anti-inflammatory, anti-injury, mainly in food, health care products additives.

2. used in drugs mainly play a neuroprotective, and anti-convulsive nature.

what is palmitoylethanolamide

1. Palmitoylethanolamide is an endogenous fatty acid amide belonging to the class of nuclear transcription factor agonists. PEA has been shown to bind to nuclear receptors in the nucleus and is a natural anti-inflammatory agent for the generation and marketing of a variety of chronic pain and inflammation-related biological functions.
2. PPAR-α, a member of the peroxide proliferator-activated receptor PPARs, the other two subtypes are PPAR-β and PPARγ. PPAR-α is mainly distributed in some organs and tissues with active catabolism of fat. It is the main transcriptional regulator of fatty acid oxidase gene, which is involved in mediating lipid uptake and oxidation, and mediating amino acid metabolism. From a macroscopic point of view, it can participate in hemostasis, inflammation, lipid metabolism disorder, atherosclerosis and coronary heart disease. a pharmacological and physiological process.
3. In the animal experiments of chronic pain and inflammation models, the mechanism of action and the effect of PEA have been further verified.
4. In the model of chronic granulomatosis pain, PEA can prevent mechanical pain caused by nerve formation and germination. PEA can also inhibit the activation of ganglia, which indicates that PEA is an analgesic and anti-inflammatory substance. It is based on different mechanisms of action.
5. In the nervous system, PEA is produced as a result of the repair mechanism of chronic inflammation and chronic pain in the body. In bladder inflammation, PEA can attenuate the pain caused by visceral nerve reflexes. In the femoral nervous system, PEA achieves the effect of reducing pain perception by affecting the peripheral mast cells that promote inflammation.

PalmitoylethanolamidePacking and Storage

Packing Pack in paper-drums and two plastic bags inside. 25 Kg/Drum

PalmitoylethanolamideStorage

Store in a well-closed container away from moisture and direct sunlight.

Shelf Life 2 years if sealed and stored properly.